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KMID : 0356720100260040265
Journal of the Korean Society of Coloproctology
2010 Volume.26 No. 4 p.265 ~ p.273
Risk Factors for Anastomotic Leakage after Laparoscopic Rectal Resection
Choi Dong-Hyun

Hwang Jae-Kwan
Ko Yong-Tak
Chang Han-Jeong
Shin Hyeon-Keun
Lee Young-Chan
Lim Cheong-Ho
Jeong Seung-Kyu
Yang Hyung-Kyu
Abstract
Purpose: The anastomotic leakage rate after rectal resection has been reported to be approximately 2.5-21 percent, but most results were associated with open surgery. The aim of this study was to identify risk factors and their relationship to the experience of the surgeon for anastomotic leakage after laparoscopic rectal resection.

Methods: Between March 2003 and December 2008, 156 patients underwent a laparoscopic rectal resection without a diverting ileostomy. The patients¡¯ characteristics, the details of treatment, the intraoperative results, and the postoperative results were recorded prospectively. Univariate and multivariate analyses were applied to identify risk factors for anastomotic leakage.

Results: The majority of operations were performed for malignant disease (n = 150; 96.2%), and 96 patients (61.5%) were males. Conversion to open surgery occurred in 1 case (0.6%). The anastomotic leak rate was 10.3% (16/156), and there were no mortalities. In the univariate analysis, tumor location, anastomotic level, intraoperative events, and operation time were associated with increased anastomotic leakage rate. In the multivariate analysis, anastomotic level (odds ratio [OR], 6.855; 95% confidence interval [CI], 1.271 to 36.964) and operation time (OR, 8.115; 95% CI, 1.982 to 33.222) were significantly associated with anastomotic leakage.

Conclusion: The important risk factors for anastomotic leakage after laparoscopic rectal resection without a diverting ileostomy were low anastomosis and long operation time. An additional procedure, such as diverting stoma, may reduce the anastomotic leakage if it is selectively applied in cases with these risk factors.
KEYWORD
Anastomotic leakage, Laparoscopic surgery, Rectal resection, Risk factors
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